Prof. Dr. Nicolai Cramer


Nicolai Cramer obtained his PhD from the University of Stuttgart under the guidance of Sabine Laschat in 2005. After postdoctoral studies with Barry Trost at Stanford as a Feodor-Lynen scholar, he started in 2007 his independent career as Habilitant associated to the chair of Erick Carreira at the ETH Zurich. He recieved his venia legendi in 2010 and subsequently moved to EPFL as Assistant Professor. Nicolai was promoted to Associate Professor in 2013 and subsequently to Full Professor in 2015. His research interests encompass enantioselective metal-catalyzed transformations and their implementation for the synthesis of biologically active molecules. A key focus of his research is the development of asymmetric C-H bond functionalizations and the design of broadly useful chiral ligands.

Contact information

Laboratory of Asymmetric Catalysis and Synthesis, Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland. nicolai.cramer@epfl.ch

My Sessions

Chiral Cyclopentadienyls: Enabling Ligands for Broad Range of Asymmetric C-H Functionalizations


Reactions involving the selective activation and subsequent functionalization of C-H bonds have a high synthetic potential because of their economic and ecological benefits. Despite significant progress in addressing reactivity and selectivity issues, as well as refining mechanistic understanding of the different pathways, catalytic enantioselective transformations remain an underdeveloped and challenging task. Often harsh conditions, the […]

Asymmetric Catalysis